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Platelet- rich plasma therapy a systematic literature review and evidence for clinical use

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Platelet-rich plasma PRP is an autologous blood-derived product with an increased concentration of platelets in plasma, which are used to deliver supraphysiological levels of growth factors. Platelet-rich plasma has been used in many fields, including oral, maxillofacial, and plastic surgery. Its use in sports medicine has been increasing after recent evidence and media publicity suggest that it may augment the treatment of muscle strains, as well as tendon and ligament healing. Basic science and animal studies show promising results, but high-level clinical trials have yet to prove its efficacy. With increasing media coverage on the use of PRP in athletes, it is paramount that orthopedic surgeons and sports medicine physicians understand the various methods of preparation and administration, potential clinical applications, and available clinical results to best counsel patients on its advantages and disadvantages. Abstract Platelet-rich plasma PRP is an autologous blood-derived product with an increased concentration of platelets in plasma, which are used to deliver supraphysiological levels of growth factors.
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The use of platelet-rich plasma to enhance the outcomes of implant therapy: A systematic review

Platelet- rich plasma therapy a systematic literature review and evidence for clinical use
Platelet- rich plasma therapy a systematic literature review and evidence for clinical use
Platelet- rich plasma therapy a systematic literature review and evidence for clinical use
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The use of platelet-rich plasma to enhance the outcomes of implant therapy: A systematic review

Metrics details. Platelet-rich Plasma PRP is a fascinating biological treatment showing promising results for the management of cartilage disorders. However, despite the step forwards in this research area and the increasing use of PRP in clinical practice, its use remains still controversial and especially its application as injective treatment for ankle cartilage pathology have been scarcely investigated. The aim of this paper is to describe the translational evidence for the use of PRP in cartilage treatment and to systematically review all the available evidence regarding the clinical application of PRP for ankle cartilage disorders, in order to understand what is the current state of the art for this specific clinical indication, underlining both limits and potential of this biological strategy. A systematic review of the clinical literature was performed on the use of PRP to treat ankle cartilage disorders and 7 papers were identified. PRP has been used in two different ways: 5 of the available papers focus on its use as an augmentation procedure to various surgical techniques for cartilage regeneration, while only two studies report its conservative application through intra-articular injections. Based on the limited number of clinical studies available on this topic, this systematic review showed the lack of major adverse events related to PRP and overall good results for the treatment of ankle cartilage pathology, thus confirming the translational potential of this biological treatment suggested by several preclinical studies.
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Platelet-rich Plasma Therapy A Systematic Literature Review And Evidence For Clinical Use

Jump to navigation. Muscle, ligament and tendon injuries frequently occur during activities such as sports, and may be due to tissue degeneration. These injuries are more frequent in particular parts of the body, such as the tendons located in the shoulder, elbow, knee and ankle. Several treatment options are available. These include conservative methods, such as physical therapy, and surgery, for example to repair torn tendons.
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Ivan Wong, M. Platelet-rich plasma PRP is an exciting and relatively new technique, which has gained a lot of interest recently for the treatment of sports injuries. This preparation can then be administered locally with the objective of allowing the growth factors released by the platelets to assist tissue healing.
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